Medical Biologist at the French Blood Establishment, Henri Mondor Hospital

Aline Floch

Aline Floch

MD, PhD. Physician-scientist specialized in transfusion medicine at the Etablissement français du sang, Henri Mondor Hospital, Creteil, the largest French Reference Laboratories for blood group genotyping and part of the research team “Transfusion and red blood cell diseases”, directed by Prof. France Pirenne, Institut Mondor de Recherche Biomédicale, Université Paris Est-Créteil. 

Her research interests include the RH blood group system (previously “Rhesus”), the transfusion of patients with sickle cell disease, and 3D modeling of blood group proteins to better understand them.

She teaches in the SERIE "Blood transfusion and vulnerability" with Prof. France Pirenne.

Publications of Aline Floch

Pirenne F, Floch A, Diop S. Alloimmunisation against red blood cells in sickle cell disease: transfusion challenges in high-income and low-income countries. Lancet Haematol. 2023 Apr 12:S2352-3026(23)00066-2. doi: 10.1016/S2352-3026(23)00066-2. Epub ahead of print. PMID: 37060916.

Floch A, Téletchéa S, Tournamille C, de Brevern AG, Pirenne F. A Review of the Literature Organized Into a New Database: RHeference. Transfus Med Rev. 2021 Apr;35(2):70-77. doi: 10.1016/j.tmrv.2021.04.002. Epub 2021 Apr 20. PMID: 33994075.

Floch A. Maternal red blood cell alloimmunisation Working Party, literature review. RH blood group system: Rare specificities. Transfus Clin Biol. 2021 Aug;28(3):314-320. doi: 10.1016/j.tracli.2021.04.007. Epub 2021 Apr 22. PMID: 33895380.

Floch A, Pirenne F, Barrault A, Chami B, Toly-Ndour C, Tournamille C, de Brevern AG. Insights into anti-D formation in carriers of RhD variants through studies of 3D intraprotein interactions. Transfusion. 2021 Apr;61(4):1286-1301. doi: 10.1111/trf.16301. Epub 2021 Feb 14. PMID: 33586199.

Floch A, Morel A, Zanchetta-Balint F, Cordonnier-Jourdin C, Allali S, Grall M, Ithier G, Carpentier B, Pakdaman S, Merle JC, Goulabchand R, Khalifeh T, Berceanu A, Helmer C, Chantalat-Auger C, Frémeaux-Bacchi V, Michel M, de Montalembert M, Mekontso-Dessap A, Pirenne F, Habibi A, Bartolucci P. Anti-C5 antibody treatment for delayed hemolytic transfusion reactions in sickle cell disease. Haematologica. 2020 Nov 1;105(11):2694-2697. doi: 10.3324/haematol.2020.253856. PMID: 33131265; PMCID: PMC7604638.

SERIE of Aline Floch