Summer School 2025 [September 25th and 26th]: Senescence and Aging: From Molecular Mechanisms to Multiscale Interventions

Summer School 2025 [September 25th and 26th]: Senescence and Aging: From Molecular Mechanisms to Multiscale Interventions

Upcoming Events

Published on 20 juin 2025

Summer School 2025 : 

Senescence and Aging: From Molecular Mechanisms to Multiscale Interventions

Mandatory registration: https://forms.cloud.microsoft/e/ztV1DS8GPB

We are excited to announce the Summer School 2025, which continues our tradition of addressing topics related to aging. This year's event is titled "Senescence and Aging: From Molecular Mechanisms to Multi-Scale Interventions.

The event will take place at the Biomedical Research Building, Faculty of Health, UPEC, 8 rue du Général Sarrail, 94000 Créteil. 

Join leading experts and rising stars in aging and senescence research at this groundbreaking two-day conference, bringing together the latest discoveries, innovative technologies, and therapeutic advances to unravel the complex biology of aging and senescence. Whether your expertise lies in molecular biology, computational modeling, clinical research, or public health, this conference offers a unique interdisciplinary platform to explore aging from cells to society.

EUR LIVE is organizing the Summer School 2025 with esteemed European universities, including the University of Glasgow, the University of Federico II of Naples, and the European University Alliance Aurora. We look forward to welcoming many of you for two days of conferences and engaging discussions.

We look forward to seeing many of you for these two days of conferences, and discussions.

Why Attend?

Cutting-Edge Science: Dive deep into the molecular and cellular mechanisms driving senescence and aging, including epigenetic clocks, mitochondrial dynamics, and immune system interactions.

Innovative Technologies: Discover how spatial multiomics, big data analytics, and precision epigenetic editing are revolutionizing aging research.

Translational Insights: Explore therapeutic strategies targeting senescent cells, including senolytic co-targeting in cancer and cardiac aging, and immune-mediated clearance approaches.

Systems and Public Health Perspectives: Understand how integrative models and public strategies can inform interventions to slow aging at the organismal and population levels.

Networking and Collaboration: Connect with top scientists, clinicians, and policymakers. Participate in panel discussions and roundtables focused on the future of aging research.

Emerging Talent Spotlight: Engage with tomorrow’s leaders during flash talk sessions showcasing innovative early-career research.

Featured Sessions Include:

Cellular Senescence as a Systems-Level Driver of Aging and Disease

Multiscale Discovery Platforms: From Natural Products to Spatial Omics

Quantifying and Reprogramming Aging: Big Data and Epigenetic Clocks

Therapeutic Targeting of Senescence: Organ Interfaces and Immune Surveillance

From Cellular Aging to Public Health: Integrative Approaches to Slow Senescence

Keynote Speaker

Clemens Schmitt — Pioneer in senotherapies co-targeting cancer and aging.

Who Should Attend?

Researchers in molecular biology, genetics, epigenetics, immunology, bioinformatics, pharmacology, clinical sciences, and public health, as well as biotech innovators and policymakers interested in aging and age-related diseases.

Mandatory registration: https://forms.cloud.microsoft/e/ztV1DS8GPB

Program: 

Day 1: Senescence and Aging: Mechanisms, Disease Links, and Translational Horizons

Early Morning Session: Opening & Keynote Address 

  • 8:00 AM - 8:45 AM: Registration
  • 8:45 AM - 9:00 AM: Conference Opening & Introduction to the Theme and Focus Areas
  • 9:00 AM - 10:00 AM: Keynote Address: Clemens Schmitt: "Senolytic Co-targeting of Cancer and Aging"

10:00 AM - 10:30 AM: Coffee Break

Late Morning Session: Cellular Senescence as a Systems-Level Driver of Aging and Disease 

  • 10:30 AM - 11:00 AM: Soni Savai: "Age-Associated Genetic, Epigenetic, and Metabolic Changes in Lung Diseases: Driver or Bystander?"
  • 11:00 AM - 11:30 AM: Utz Herbig: "Senescent T Cells: Immunological Clocks and Architects of Age-Associated Diseases"
  • 11:30 AM - 12:00 PM: Alex Chang: "Leaky Mitochondria Driving Mitochondrial Hyperfusion and Myocardial Senescence"
  • 12:00 PM - 12:30 PM: Julien Cherfils: "Immunomodulation Triggered by Senescent Cells: From Senescence-Associated Immune Checkpoint (SIC) to New Medical Applications"

12:30 PM - 2:00 PM: Lunch Break & Poster Viewing I

Afternoon Session: Clinical Implications of the Aging Process – Flash Talks 

  • 2:00 PM - 3:00 PM: Tomorrow’s Scientists: Flash Talks (10' presentation followed by 2' of discussion)

Late Afternoon Session I: Therapeutic Targeting of Senescence: Organ Interfaces and Immune Surveillance 

  • 3:00 PM - 3:30 PM: Stefanie Dimmeler: "Targeting Senescence to Prevent Cardiac Aging: Impact on the Neurovascular Interface"

3:30 PM - 4:00 PM: Coffee Break

  • 4:00 PM - 4:30 PM: Jesus Gil: "Enhancing Immune-Mediated Killing of Senescent Cells"
  • 4:30 PM – 5:00 PM: Pasquale Maffia: "Immune Dysregula3on in Cardiovascular Disease – From Novel Mechanisms to Therapeutic Targeting"

Late Afternoon Session II: From Cellular Aging to Public Strategies: Integrative Approaches to Slowing Senescence 

  • 5:00 PM - 5:30 PM: Maël Lemoine: "Can the Aging of an Organism be Reduced to the Aging of its Cells?"
  • 5:30 PM - 6:00 PM: Didier Coeurnelle: “Big Health Data Analyzed with a Focus on Biological Insights to Slow Down Senescence: How Public Institutions Could and Should Work for this Goal”

Day 2: Mapping and Modulating Aging: From Molecular Discovery to Systems Integration

Early Morning Session: Multiscale Discovery Platforms: From Natural Compounds to Spatial Omics 

  • 8:30 AM - 9:00 AM: Laurent Meijer: "From Sea to Pharmacy: From the Marine Sponge Natural Product Leucettamine B to DYRK1A Kinase Inhibitors, a Family of Clinical Drugs for Multiple Therapeutic Indications"
  • 9:00 AM - 9:30 AM: Christoph Kuppe: "Spatial Multiomics Uncover Novel Cardiomyocyte Signatures Relevant for Human Heart Disease"

9:30 AM - 10:00 AM: Coffee Break

Late Morning Sessions: Systems Biology of Aging: Predictive Models, Cellular Phenotypes, and Epigenetic Clocks 

  • 10:00 AM - 10:30 AM: Isabelle ADER-PERARNAU: “Multiscale Approach to Identify Health Markers Related to Aging”
  • 10:30 AM – 11:00 AM: Wolfgang WAGNER: "Resetting the Epigenetic Clock: Epigenetic Editing at Individual Age-associated CpGs Affects the Genome-wide Epigenetic Aging Landscape": 
  • 11:00 AM – 11:30 AM: Vincent GELI: “The Multiple Faces of TERT in Aging and Cancer”
  • 11:30 AM – 12:00 PM: Jing Ye: “Unveiling an Age-Related Cardiomyocyte Change Serving as a Breeding Ground for Heart Failure”
  • 12:00 PM - 1:00 PM: Tomorrow’s Scientists: Flash Talks (10' presentation followed by 2' of discussion)

1:00 PM - 2:30 PM: Lunch Break & Poster Viewing II

2:30 PM - 3:30 PM: Tomorrow’s Scientists: Flash Talks (10' presentation followed by 2' of discussion)

Afternoon Session: Challenges, Future Directions, and Collaborations 

Closing Session: Multidisciplinary Future of Aging Research

  • 3:30 PM - 4:30 PM: Round Table Discussion: Thierry Galli (ITMO, INSERM), Yvan de Launoit (CNRS), Eric Gilson (Institute for Research on Cancer and Aging Nice - IRCAN)
    • The Future of Aging Research—Interdisciplinary Approaches
      • Reflect on key findings and future research, policy, and societal directions.
      • Creation of a "Biology of Aging Society"

4:30 PM - 4:45 PM: Closing Remarks & Key Takeaways

Mandatory registration: https://forms.cloud.microsoft/e/ztV1DS8GPB

Update 31 oct. 2023

Share: